ChemicalBook--->CAS DataBase List--->147695-92-9

147695-92-9

147695-92-9 Structure

147695-92-9 Structure
IdentificationBack Directory
[Name]

N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE
[CAS]

147695-92-9
[Synonyms]

ZM 226600
N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE
Propanamide, 3,3,3-trifluoro-2-hydroxy-2-methyl-N-[4-(phenylsulfonyl)phenyl]-
[Molecular Formula]

C16H14F3NO4S
[MDL Number]

MFCD09266222
[MOL File]

147695-92-9.mol
[Molecular Weight]

373.35
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[solubility ]

Soluble to 100 mM in DMSO
[form ]

Off-white solid.
[color ]

White to off-white
[InChI]

InChI=1S/C16H14F3NO4S/c1-15(22,16(17,18)19)14(21)20-11-7-9-13(10-8-11)25(23,24)12-5-3-2-4-6-12/h2-10,22H,1H3,(H,20,21)
[InChIKey]

LJLXQHHFAKVTNP-UHFFFAOYSA-N
[SMILES]

C(NC1=CC=C(S(C2=CC=CC=C2)(=O)=O)C=C1)(=O)C(O)(C)C(F)(F)F
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard InformationBack Directory
[Uses]

ZM 226600, is a potent KIR (Kir6, KATP) channel opener (EC50 = 0.5 μM), devoid of antiandrogen properties.
[Definition]

ChEBI: N-[4-(benzenesulfonyl)phenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide is an anilide.
[in vivo]

ZM226600 (10-1000 nmol/kg, i.v.) does not alter significantly the heart beats rate in anaesthetized rats[1].

[storage]

Store at RT
Spectrum DetailBack Directory
[Spectrum Detail]

N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE(147695-92-9)1HNMR
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