| Identification | Back Directory | [Name]
METHYL ACETIMIDATE HCL | [CAS]
14777-29-8 | [Synonyms]
methyl acetimidate
methylethanimidate
1-Methoxyethanimine
Acetimidic acid methyl
1-Methoxy-1-ethanimine
acetimidicacid,methylester
ethanimidicacid,methylester
Ethanimidic acid, methyl ester (9CI) | [Molecular Formula]
C3H7NO | [MDL Number]
MFCD01941513 | [MOL File]
14777-29-8.mol | [Molecular Weight]
73.0938 |
| Hazard Information | Back Directory | [Uses]
Methyl acetimidate is an imidoester that can inhibit the formation of sickle cells. Methyl acetimidate enhances the oxygen affinity and gelling properties of high molecular weight hemoglobin (HMW Hb) by modifying the amino groups of hemoglobin, thereby suppressing the formation of sickle cells. Methyl acetimidate can be used in research related to anemia[1]. | [References]
[1] Chao TL, et al. Inhibition of sickling by methyl acetimidate. FEBS Lett. 1976 Feb 1;62(1):57-9. doi: 10.1016/0014-5793(76)80015-4. DOI:10.1016/0014-5793(76)80015-4
[2] Chao TL, et al. The effects of oxygen affinity and gelation of hemoglobin S crosslinked by reaction with methyl acetimidate. Hemoglobin. 1981;5(1):47-72. DOI:10.3109/03630268108996910 |
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