| Identification | Back Directory | [Name]
m-PEG4-succinimidyl carbonate | [CAS]
147912-03-6 | [Synonyms]
m-PEG4-O-NHS ester
m-PEG4-succinimidyl carbonate
2,5,8,11,14-Pentaoxapentadecanoic acid, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C14H23NO9 | [MDL Number]
MFCD30828679 | [MOL File]
147912-03-6.mol | [Molecular Weight]
349.33 |
| Hazard Information | Back Directory | [Description]
m-PEG4-succinimidyl carbonate is a PEG linker containing a succinumidyl carbonate group. The succinimidyl carbonate group is a good leaving group and commonly reacts with amine nucleophiles. | [Uses]
m-PEG4-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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