ChemicalBook--->CAS DataBase List--->14812-59-0

14812-59-0

14812-59-0 Structure

14812-59-0 Structure
IdentificationBack Directory
[Name]

2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE
[CAS]

14812-59-0
[Synonyms]

2-chloro-4,4,5,5-tetramethyl-1,3,2-dioxa-phosphol
2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE
1,3,2-Dioxaphospholane, 2-chloro-4,4,5,5-tetramethyl-
2-Chloro-4,4,5,5-tetraMethyl-1,3,2-dioxaphospholane 95%
[Molecular Formula]

C6H12ClO2P
[MDL Number]

MFCD00274239
[MOL File]

14812-59-0.mol
[Molecular Weight]

182.59
Chemical PropertiesBack Directory
[Boiling point ]

81.5-82 °C13 mm Hg(lit.)
[density ]

1.149 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.471(lit.)
[Fp ]

>230 °F
Safety DataBack Directory
[Symbol(GHS) ]


GHS05
[Signal word ]

Danger
[Hazard statements ]

H314
[Precautionary statements ]

P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
[Hazard Codes ]

C
[Risk Statements ]

14-34
[Safety Statements ]

22-26-27-36/37/39-45
[RIDADR ]

UN 3265 8/PG 2
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane(14812-59-0) is an organic reagent commonly used in chemical and experimental research as a reagent for the phosphorylation of alcohols and heteroatoms for the formation of glycosyl donors and ligands, and in analytical studies of derivatised lignin samples. It is also used as a catalyst in CuO/TiO2 catalysed lignin oxidation studies.
[Chemical Properties]

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane is an organic reagent in the physical state of a solid. Molecular weight: 182.59, Density: 1.149 g/cm3, Boiling point: 81.5-82° C (lit.) at 13 mmHg, Flash point: 113 °C, Refractive index: n20/D 1.471 (lit.), Store at 10°C-25°C, keep dry, under inert gas nitrogen.
[Uses]

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (TMDP,14812-59-0) can be used:
  • As a reagent for the phosphitylation of alcohols and heteroatomic nucleophiles, resulting in the formation of useful glycosyl donors and ligands.
  • As a phosphitylation reagent to derivatize lignin samples for 31P NMR analysis.

[reaction suitability]

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
Spectrum DetailBack Directory
[Spectrum Detail]

2-CHLORO-4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLANE(14812-59-0)FT-IR
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