| Identification | Back Directory | [Name]
2-BROMO-5-(TRIFLUOROMETHYL)BENZOIC ACID | [CAS]
1483-56-3 | [Synonyms]
4-Bromo-3-carboxybenzotrifluoride, 6-Bromo-alpha,alpha,alpha-trifluoro-m-toluic acid | [Molecular Formula]
C8H4BrF3O2 | [MDL Number]
MFCD06208253 | [MOL File]
1483-56-3.mol | [Molecular Weight]
269.02 |
| Chemical Properties | Back Directory | [Melting point ]
116-117℃ | [Boiling point ]
301.0±42.0 °C(Predicted) | [density ]
1.773 | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Solid | [pka]
2.42±0.10(Predicted) | [Appearance]
White to off-white Solid | [Water Solubility ]
Slightly soluble in water. | [InChI]
InChI=1S/C8H4BrF3O2/c9-6-2-1-4(8(10,11)12)3-5(6)7(13)14/h1-3H,(H,13,14) | [InChIKey]
REBQGRPKXYIJDC-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC(C(F)(F)F)=CC=C1Br | [CAS DataBase Reference]
1483-56-3 |
| Hazard Information | Back Directory | [Chemical Properties]
off-white powder | [Uses]
2-Bromo-5-(trifluoromethyl)benzoic acid is used as an organic synthesis reagent or pharmaceutical intermediate compound. | [Synthesis]
2,2,6,6-tetramethylhexahydropiperidine (22.5 ml, 133.4 mmol) was added to a solution of n-BuLi (26.7 ml of a 2.5 M solution in tetrahydrofuran (THF), 66.7 mmol) in THF (130 ml) at -78 °C. The mixture was stirred at -78 °C for 30 min and then carefully low |
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