ChemicalBook--->CAS DataBase List--->148504-51-2

148504-51-2

148504-51-2 Structure

148504-51-2 Structure
IdentificationBack Directory
[Name]

Ripisartan
[CAS]

148504-51-2
[Synonyms]

UP 269-6
Ripisartan
5-Methyl-7-n-propyl-8-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-(1,2,4)-triazolo(1,5-c)pyrimidin-2(3H)-one
[1,2,4]Triazolo[1,5-c]pyrimidin-2(3H)-one, 5-methyl-7-propyl-8-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
[Molecular Formula]

C23H22N8O
[MDL Number]

MFCD00917221
[MOL File]

148504-51-2.mol
[Molecular Weight]

426.47
Hazard InformationBack Directory
[Uses]

Ripisartan (UP-2696) is an angiotensin II receptor antagonist. Ripisartan is orally available. Ripisartan binds to angiotensin II receptors, dilates blood vessels, and lowers blood pressure[1].
[IC 50]

AT2 Receptor
[References]

[1] Virone-Oddos A, et al. In vitro and in vivo effects of UP 269-6, a new potent orally active nonpeptide angiotensin II receptor antagonist, on vascular smooth muscle cell proliferation. Br J Pharmacol. 1997 Feb;120(3):488-94. DOI:10.1038/sj.bjp.0700897
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