ChemicalBook--->CAS DataBase List--->148505-03-7

148505-03-7

148505-03-7 Structure

148505-03-7 Structure
IdentificationBack Directory
[Name]

GRK2i
[CAS]

148505-03-7
[Synonyms]

GRK2i
L-Serine, L-tryptophyl-L-lysyl-L-lysyl-L-α-glutamyl-L-leucyl-L-arginyl-L-α-aspartyl-L-alanyl-L-tyrosyl-L-arginyl-L-α-glutamyl-L-alanyl-L-glutaminyl-L-glutaminyl-L-leucyl-L-valyl-L-glutaminyl-L-arginyl-L-valyl-L-prolyl-L-lysyl-L-methionyl-L-lysyl-L-asparaginyl-L-lysyl-L-prolyl-L-arginyl- (9CI)
[Molecular Formula]

C153H256N50O41S
[MDL Number]

MFCD16621671
[MOL File]

148505-03-7.mol
[Molecular Weight]

3484.05
Chemical PropertiesBack Directory
[density ]

1.49±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Powder
[Water Solubility ]

Soluble to 2 mg/ml in water
Hazard InformationBack Directory
[Uses]

GRK2i is a Gβγ-inhibitory peptide that selectively prevents Gβγ-mediated signaling. GRK2i corresponds to the Gβγ-binding domain of GRK2 (G-protein-coupled receptor kinase 2)[1].
[storage]

Store at -20°C
[References]

[1] Jorge A Sierra-Fonseca, et al. Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction. BMC Neurosci. 2014 Dec 31;15:132. DOI:10.1186/s12868-014-0132-4
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