| Identification | Back Directory | [Name]
Ternatin heptapeptide | [CAS]
148619-41-4 | [Synonyms]
Ternatin heptapeptide
Cyclo[N-methyl-L-alanyl-N-methyl-D-alanyl-(3R)-3-hydroxy-D-leucyl-D-alloisoleucyl-N-methyl-L-alanyl-N-methyl-L-leucyl-L-leucyl] | [Molecular Formula]
C37H67N7O8 | [MDL Number]
MFCD29924702 | [MOL File]
148619-41-4.mol | [Molecular Weight]
737.97 |
| Chemical Properties | Back Directory | [Boiling point ]
985.4±65.0 °C(Predicted) | [density ]
1.028±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
A solid | [pka]
12.83±0.70(Predicted) | [Sequence]
Cyclo({Ala(N-Me)}-{d-Ala((N-Me)}-{d-Leu((3R)-3-hydroxy)}-{d-Ile}-{Ala(N-Me)}-Leu-Leu) |
| Hazard Information | Back Directory | [Uses]
Ternatin heptapeptide is a cyclic peptide antifungal metabolite, first isolated from the fungus Didymocladium ternatum in Russia in 1974. More recently, Ternatin heptapeptide has been demonstrated to be a potent inhibitor of fat accumulation in 3T3-L1 murine adipocytes. Note that this metabolite should not be confused with the plant flavonoid of the same name.
| [Uses]
Ternatin is an inhibitor of fat accumulation in 3T3-L1 murine adipocytes.. |
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