ChemicalBook--->CAS DataBase List--->1491150-22-1

1491150-22-1

1491150-22-1 Structure

1491150-22-1 Structure
IdentificationBack Directory
[Name]

3-Pyridinecarboxamide, 5-bromo-6-chloro-N-[4-(chlorodifluoromethoxy)phenyl]-
[CAS]

1491150-22-1
[Synonyms]

3-Pyridinecarboxamide, 5-bromo-6-chloro-N-[4-(chlorodifluoromethoxy)phenyl]-
[Molecular Formula]

C13H7BrCl2F2N2O2
[MOL File]

1491150-22-1.mol
[Molecular Weight]

412.01
Chemical PropertiesBack Directory
[Boiling point ]

399.0±42.0 °C(Predicted)
[density ]

1.745±0.06 g/cm3(Predicted)
[pka]

10.00±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

5-Bromo-6-chloro-n-(4-(chlorodifluoromethoxy)phenyl)nicotinamide is a pharmaceutical intermediate compound used in the preparation of the anti-tumour drug Asciminib. Asciminib is a tyrosine kinase inhibitor (TKI) indicated for the treatment of chronic phase Philadelphia chromosome-positive chronic myeloid leukaemia (Ph+ CML).
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