| Identification | Back Directory | [Name]
(S)-Maleoyl-DPR(Boc)-OH·DCHA | [CAS]
1491152-23-8 | [Synonyms]
mDPR(boc)
Mal-L-PA-NH-Boc
Mal-Dap(Boc)·DCHA
Mal-Dpr(Boc)·DCHA
Mal-L-Dap(Boc)-OH
Mal-L-Dap(Boc)-OH·DCHA≥99%
(S)-Maleoyl-DPR(Boc)-OH·DCHA
(S)-3-(Boc-amino)-2-(2,5-dioxo-2,5-dihydro-1-pyrrolyl)propanoic Acid
(S)-3-((tert-Butoxycarbonyl)amino)-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid
1H-Pyrrole-1-acetic acid, α-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-2,5-dihydro-2,5-dioxo-, (αS)- | [Molecular Formula]
C12H16N2O6 | [MDL Number]
MFCD28100921 | [MOL File]
1491152-23-8.mol | [Molecular Weight]
284.27 |
| Chemical Properties | Back Directory | [Boiling point ]
494.4±40.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.03±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | [IC 50]
Non-cleavable Linker | [References]
[1] Robert Lyon, et al. Self-stabilizing linker conjugates. WO2013173337A2. |
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