| Identification | Back Directory | [Name]
CGP 54626 HYDROCHLORIDE | [CAS]
149184-21-4 | [Synonyms]
CGP 54626
[3H]-CGP54626
CGP-54626 HCl
CGP 54626 HYDROCHLORIDE
TOC CGP 54626 Hydrochloride
[S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl)phosphinicacid
(S-(R*,R*))-(3-((1-(3,4-Dichlorophenyl)ethyl)amino)-2-hydroxypropyl)-([3.4-3H]-cyclohexylmethyl)phosphinicacid
[S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl)phosphinic acid hydrochloride
[S-(R*,R*)]-[3-[[1-(3,4-DICHLOROPHENYL)ETHYL]AMINO]-2-HYDROXYPROPYL](CYCLOHEXYLMETHYL) PHOSPHINIC ACID HYDROCHLORIDE | [Molecular Formula]
C18H27Cl2NO3PT | [MDL Number]
MFCD09878291 | [MOL File]
149184-21-4.mol | [Molecular Weight]
410.31 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at RT | [solubility ]
DMF: 0.33 mg/ml; DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml; Ethanol: 0.2 mg/ml | [form ]
A crystalline solid | [color ]
White | [InChIKey]
ZQCFHOVIXCJPLE-LINSIKMZSA-N | [SMILES]
ClC1=C(C=CC([C@@H](NC[C@@H](CP(CC2CCCCC2)(O)=O)O)C)=C1)Cl.Cl |
| Hazard Information | Back Directory | [Description]
CGP 54626 is a selective antagonist of the GABAB receptor with an IC50 value of 4 nM. It can be used to investigate the role of GABAB receptors in neurological signaling. | [Uses]
CGP 54626 (hydrochloride) is a selective antagonist of GABAB receptor with an IC50 value of 4 nM. CGP 54626 (hydrochloride) can be used to investigate the role of GABAB receptors in neurological signaling[1]. | [Biological Activity]
A potent, selective GABA B receptor antagonist (IC 50 = 4 nM). | [storage]
Store at -20°C | [References]
[1] Kaupmann K, et al. GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature. 1998 Dec 17;396(6712):683-7. DOI:10.1038/25360 |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|