| Identification | Back Directory | [Name]
H-ARG-PHE-TYR-VAL-VAL-MET-TRP-LYS-OH | [CAS]
149234-04-8 | [Synonyms]
Thrombospondin-1 (1016-1023)
ARG-PHE-TYR-VAL-VAL-MET-TRP-LYS
H-ARG-PHE-TYR-VAL-VAL-MET-TRP-LYS-OH
TS1 (1016-1023) (HUMAN, BOVINE, MOUSE)
THROMBOSPONDIN-1 (1016-1023) (HUMAN, BOVINE, MOUSE)
L-Arginyl-L-phenylalanyl-L-tyrosyl-L-valyl-L-valyl-L-methionyl-L-tryptophyl-L-lysine
L-Lysine, L-arginyl-L-phenylalanyl-L-tyrosyl-L-valyl-L-valyl-L-methionyl-L-tryptophyl- | [Molecular Formula]
C56H81N13O10S | [MDL Number]
MFCD00237794 | [MOL File]
149234-04-8.mol | [Molecular Weight]
1128.39 |
| Hazard Information | Back Directory | [Uses]
Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide[1]. | [References]
[1] Chih-Jian Lih, et al. Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes. Genes Dev. 2006 Aug 1;20(15):2082-95. DOI:10.1101/gad.1441306
[2] U Johansson, et al. CD47 ligation induces a rapid caspase-independent apoptosis-like cell death in human monocytes and dendritic cells. Scand J Immunol. 2004 Jan;59(1):40-9. DOI:10.1111/j.0300-9475.2004.01355.x |
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