| Identification | Back Directory | [Name]
H-ILE-ARG-VAL-VAL-MET-OH | [CAS]
149234-05-9 | [Synonyms]
IRVVM
ILE-ARG-VAL-VAL-MET
H-ILE-ARG-VAL-VAL-MET-OH
L-Isoleucyl-L-arginyl-L-valyl-L-valyl-L-methionine
L-Methionine, L-isoleucyl-L-arginyl-L-valyl-L-valyl- | [Molecular Formula]
C27H52N8O6S | [MDL Number]
MFCD00238000 | [MOL File]
149234-05-9.mol | [Molecular Weight]
616.82 |
| Hazard Information | Back Directory | [Uses]
H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide from C7 with a domain that supports cell attachment. H-ILE-ARG-VAL-VAL-MET-OH is also the sequence fragment that binds to the thrombospondin-1 (TS1) receptor[1][2]. | [References]
[1] Kosfeld MD, et al. Identification of a new cell adhesion motif in two homologous peptides from the COOH-terminal cell binding domain of human thrombospondin. J Biol Chem. 1993 Apr 25;268(12):8808-14. PMID:8473325
[2] Frazier, et al. Thrombospondin 1 subfragments that bind to thrombospondin 1 receptor and inhibit cell adhesion: United States, US5399667[P]. 1995-03-21. |
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