| Identification | Back Directory | [Name]
adenoregulin | [CAS]
149260-68-4 | [Synonyms]
adenoregulin
L-Valine, glycyl-L-leucyl-L-tryptophyl-L-seryl-L-lysyl-L-isoleucyl-L-lysyl-L-α-glutamyl-L-valylglycyl-L-lysyl-L-α-glutamyl-L-alanyl-L-alanyl-L-lysyl-L-alanyl-L-alanyl-L-alanyl-L-lysyl-L-alanyl-L-alanylglycyl-L-lysyl-L-alanyl-L-alanyl-L-leucylglycyl-L-alanyl-L-valyl-L-seryl-L-α-glutamyl-L-alanyl- | [Molecular Formula]
C142H242N40O42 | [MOL File]
149260-68-4.mol | [Molecular Weight]
3181.68 |
| Chemical Properties | Back Directory | [Boiling point ]
2798.1±65.0 °C(predicted) | [density ]
1.264±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [Sequence]
Gly-Leu-Trp-Ser-Lys-Ile-Lys-Glu-Val-Gly-Lys-Glu-Ala-Ala-Lys-Ala-Ala-Ala-Lys-Ala-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Val-Ser-Glu-Ala-Val |
| Hazard Information | Back Directory | [Uses]
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor[1]. | [References]
[1] Mor A, et al. Isolation and structure of novel defensive peptides from frog skin. Eur J Biochem. 1994 Jan 15;219(1-2):145-54. DOI:10.1111/j.1432-1033.1994.tb19924.x
[2] Baek HJ, et al. Ligand binding inhibitors of A1 adenosine receptor from Rana rugosa are phospholipase A2s. Eur J Biochem. 2000 Mar;267(5):1340-6. DOI:10.1046/j.1432-1327.2000.01102.x |
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