149438-56-2

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149438-56-2 Structure

Identification	Back Directory
[Name] N,S-BIS-FMOC-GLUTATHIONE
[CAS] 149438-56-2
[Synonyms] FMOC-GLU(CYS(FMOC)-GLY) N,S-BIS-FMOC-GLUTATHIONE FMOC-GLU(CYS(FMOC)-GLY-OH)-OH N,S-BIS-FMOC-GLUTATHIONE USP/EP/BP N,S-Bis-Fmoc-glutathione Fmoc-Glu(Cys(Fmoc)-Gly-OH)-OH N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-γ-glutamyl-S-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteinylglycine Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-γ-glutamyl-S-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteinyl- N-[S-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-gamma-glutamyl]-L-cysteinyl]glycine
[Molecular Formula] C40H37N3O10S
[MDL Number] MFCD00798635
[MOL File] 149438-56-2.mol
[Molecular Weight] 751.8

Chemical Properties	Back Directory
[density ] 1.392
[storage temp. ] -15°C
[form ] Solid
[pka] 3.20±0.10(Predicted)
[color ] White to off-white
[Sequence] {Fmoc}-{γ-Glu(({Cys-Fmoc})-Gly)}

Hazard Information	Back Directory
[Uses] N,S-Bis-Fmoc-Glutathione is a potent glyoxalase II inhibitor with a Ki value of 0.75 μM and an IC50 of 2.5 μM[1].
[References] [1] Norton SJ, et al. Inhibitors and inhibition studies of mammalian glyoxalase II activity. Biochem Soc Trans. 1993 May;21(2):545-9. DOI:10.1042/bst0210545

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