| Identification | Back Directory | [Name]
1H-Indole-5-carboxamide, N-(3,4-dichlorophenyl)- | [CAS]
1494477-03-0 | [Synonyms]
PSB-1410
1H-Indole-5-carboxamide, N-(3,4-dichlorophenyl)- | [Molecular Formula]
C15H10Cl2N2O | [MOL File]
1494477-03-0.mol | [Molecular Weight]
305.16 |
| Chemical Properties | Back Directory | [Boiling point ]
414.8±40.0 °C(Predicted) | [density ]
1.491±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
12.27±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
PSB-1410 is a potent, selective, competitive, and reversible inhibitor of monoamine oxidase B (MAO-B). | [Uses]
PSB-1410 is a selective and competitive monoamine oxidase B (MAO-B) inhibitor with IC50 for human MAO-B and rat MAO-B Values are 0.23 and 1.01 nM respectively[1]. | [IC 50]
hMAO-B: 0.23 nM (IC50); rMAO-B: 1.01 nM (IC50) | [References]
[1] Tzvetkov NT, et al. Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency. J Med Chem. 2014 Aug 14;57(15):6679-703. DOI:10.1021/jm500729a |
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