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1494676-74-2

1494676-74-2 Structure

1494676-74-2 Structure
IdentificationBack Directory
[Name]

2,4-Thiazolidinedione, 3-[[4-(1,1-dimethylethyl)phenyl]methyl]-5-[(4-hydroxy-3-nitrophenyl)methylene]-
[CAS]

1494676-74-2
[Synonyms]

LH65.3
LH-65.3
LH 65.3
2,4-Thiazolidinedione, 3-[[4-(1,1-dimethylethyl)phenyl]methyl]-5-[(4-hydroxy-3-nitrophenyl)methylene]-
[Molecular Formula]

C21H20N2O5S
[MOL File]

1494676-74-2.mol
[Molecular Weight]

412.46
Chemical PropertiesBack Directory
[Boiling point ]

554.6±60.0 °C(Predicted)
[density ]

1.396±0.06 g/cm3(Predicted)
[pka]

5.92±0.35(Predicted)
Hazard InformationBack Directory
[Description]

LH65.3 is an S. typhimurium infection inhibitor on the activity of DUSP3, DUSP11, and DUSP27.
[Uses]

LH65.3 is a compound with the potential to modulate bacterial infection that was identified through integrated small interfering RNA and small molecule screening to control bacterial infection, involving the regulation of multiple kinases and phosphatases.
[References]

[1] Integrating chemical and genetic silencing strategies to identify host kinase-phosphatase inhibitor networks that control bacterial infection DOI:10.1021/cb400421a
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