| Identification | Back Directory | [Name]
1-Azabicyclo[2.2.2]octan-3-ol, 3-[1,1'-biphenyl]-4-yl-, (+)- | [CAS]
149537-49-5 | [Synonyms]
3ACW 3-ACW 3 ACW BPH651 BPH-651 BPH 651 1-Azabicyclo[2.2.2]octan-3-ol, 3-[1,1'-biphenyl]-4-yl-, (+)- | [Molecular Formula]
C19H21NO | [MOL File]
149537-49-5.mol | [Molecular Weight]
279.38 |
| Hazard Information | Back Directory | [Description]
BPH-651 is a CrtM inhibitor. | [Uses]
BPH-651 is a compound with antibacterial activity and has the activity to inhibit dehydrosqualene synthase. BPH-651 can bind to different sites of dehydrosqualene synthase, providing structural clues for the mechanism and inhibition of head-to-head prenyltransferase, which will help future compound design. | [References]
[1] Head-to-head prenyl tranferases: anti-infective drug targets DOI:10.1021/jm300208p |
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