ChemicalBook--->CAS DataBase List--->149655-53-8

149655-53-8

149655-53-8 Structure

149655-53-8 Structure
IdentificationBack Directory
[Name]

Isomorellinol
[CAS]

149655-53-8
[Synonyms]

Isomorellinol
[Molecular Formula]

C33H38O7
[MOL File]

149655-53-8.mol
[Molecular Weight]

546.66
Chemical PropertiesBack Directory
[Boiling point ]

734.5±60.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

6.80±0.70(Predicted)
Hazard InformationBack Directory
[Description]

Isomorellinol induces apoptosis in cholangiocarcinoma (CCA)cells which is mediated through a mitochondria-dependent signaling pathway.
[Uses]

Isomorellinol is a xanthone with an anticancer potency. Isomorellinol induces apoptosis in cholangiocarcinoma cells. Isomorellinol increases the Bax/Bcl-2 protein expression ratio and decreases survivin protein expression in cholangiocarcinoma cells[1].
[References]

[1] Hahnvajanawong C, et al. Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines. World J Gastroenterol. 2010 May 14;16(18):2235-43. DOI:10.3748/wjg.v16.i18.2235
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