| Identification | Back Directory | [Name]
Lurtotecan | [CAS]
149882-10-0 | [Synonyms]
Gg 211
Nx 211
Osi 211
Osi-211
Gi 147211
Lurtotecan
Lurtotecan [inn]
RVFGKBWWUQOIOU-NDEPHWFRSA-N
11H-1,4-Dioxino(2,3-G)pyrano(3',4':6,7)indolizino(1,2-B)quinoline-9,12(8H,14H)-dione, 8-ethyl-2,3-dihydro-8-hydroxy-15-((4-methyl-1-piperazinyl)methyl)-, (8S)- | [Molecular Formula]
C28H30N4O6 | [MDL Number]
MFCD00866233 | [MOL File]
149882-10-0.mol | [Molecular Weight]
518.56 |
| Hazard Information | Back Directory | [Uses]
Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects[1]. | [IC 50]
Topoisomerase I | [References]
[1] D L Emerson, et al. In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues. Cancer Res. 1995 Feb 1;55(3):603-9. PMID:7834631 |
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| Company Name: |
LGM Pharma
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| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
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