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149882-10-0

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149882-10-0 Structure

149882-10-0 Structure
IdentificationBack Directory
[Name]

Lurtotecan
[CAS]

149882-10-0
[Synonyms]

Gg 211
Nx 211
Osi 211
Osi-211
Gi 147211
Lurtotecan
Lurtotecan [inn]
RVFGKBWWUQOIOU-NDEPHWFRSA-N
11H-1,4-Dioxino(2,3-G)pyrano(3',4':6,7)indolizino(1,2-B)quinoline-9,12(8H,14H)-dione, 8-ethyl-2,3-dihydro-8-hydroxy-15-((4-methyl-1-piperazinyl)methyl)-, (8S)-
[Molecular Formula]

C28H30N4O6
[MDL Number]

MFCD00866233
[MOL File]

149882-10-0.mol
[Molecular Weight]

518.56
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to yellow
Hazard InformationBack Directory
[Uses]

Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects[1].
[IC 50]

Topoisomerase I
[References]

[1] D L Emerson, et al. In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues. Cancer Res. 1995 Feb 1;55(3):603-9. PMID:7834631
Spectrum DetailBack Directory
[Spectrum Detail]

Lurtotecan(149882-10-0)1HNMR
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