| Chemical Properties | Back Directory | [Melting point ]
180 °C | [Boiling point ]
423.3±45.0 °C(Predicted) | [density ]
1.270±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMF: 1 mg/ml,DMSO: 2 mg/ml,Ethanol: insol,PBS (pH 7.2): insol | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Uses]
3,6-Dimethoxy-9H-xanthen-9-one is a Xanthone (HY-N0126) derivative. 3,6-Dimethoxy-9H-xanthen-9-one can be used to synthesize compounds with apoptosis-inducing activity in cancer cells[1]. | [Biological Activity]
3,6-Dimethoxy-9H-xanthen-9-one is a synthetic intermediate and a derivative of xanthone .1,2,3 It has been used in the synthesis of fluorescein derivatives, as well as compounds with anticancer or acetylcholinesterase inhibitory activities. | [storage]
-20°C | [References]
1.?ebej, P., Wintner, J., Müller, P., et al.Fluorescein analogues as photoremovable protecting groups absorbing at ~520 nmJ. Org. Chem.78(5)1833-1843(2013)
2.Liu, C., Zhang, M., Zhang, Z., et al.Synthesis and anticancer potential of novel xanthone derivatives with 3,6-substituted chainsBioorg. Med. Chem.24(18)4263-4271(2016)
3.Alawi, M.S., Awad, T.A., Mohamed, M.A., et al.Insights into the molecular basis of acetylcholinesterase inhibition by xanthones: An integrative in silico and in vitro approachMol. Simul.46(4)253-261(2020)
|
|
|