| Identification | Back Directory | [Name]
hydrochloride | [CAS]
150452-21-4 | [Synonyms]
UK 227786
UK 227786, 10 mM in DMSO
1-[4-(1,3-Benzodioxol-5-ylmethylamino)-6-chloroquinazolin-2-yl]piperidine-4-carboxylic acid | [Molecular Formula]
C22H21ClN4O4.ClH | [MOL File]
150452-21-4.mol | [Molecular Weight]
477.34 |
| Hazard Information | Back Directory | [Uses]
ER21355 hydrochloride is the hydrochloride form of ER21355 (HY-101826). ER21355 hydrochloride is an inhibitor for phosphodiesterase (PDE), which is potent for ameliorating benign prostatic hyperplasia (BPH) and prostatism through increasing levels of cAMP and cGMP, and resulting a relaxation of the smooth muscle cell[1]. | [References]
[1] Wolf-Georg Forssmann, et al. Use of phosphodiesterase inhibitors in the treatment of prostatic diseases. US 8106061B2 |
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