| Identification | Back Directory | [Name]
(D-Phe12,Nle21·38,α-Me-Leu37)-CRF (12-41) (human, rat) | [CAS]
150646-45-0 | [Synonyms]
(D-PHE12,NLE21·38,Α-ME-LEU37)-CRF(12-41)(HUMAN,RAT)
(D-Phe12,Nle21·38,α-Me-Leu37)-CRF (12-41) (human, rat)
12-41-Corticotropin-releasing factor(human),12-D-phenylalanine-21-L-norleucine-37-(2-methyl-L-leucine)-38-L-norleucine-
12-41-Corticotropin-releasing factor (human), 12-D-phenylalanine-21-L-norleucine-37-(2-methyl-L-leucine)-38-L-norleucine- (9CI) | [Molecular Formula]
C159H267N49O43 | [MDL Number]
MFCD00671446 | [MOL File]
150646-45-0.mol | [Molecular Weight]
3553.12 |
| Chemical Properties | Back Directory | [density ]
1.43±0.1 g/cm3(Predicted) | [Sequence]
{d-Phe}-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-{Nle}-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-{Leu(α-Me)}-{Nle}-Glu-Ile-Ile-NH2 |
| Hazard Information | Back Directory | [Uses]
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist. (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) prevents the IL-1a induced Luteinizing hormone (LH) inhibition[1]. | [References]
[1] Feng YJ, et al. An inhibitory effects of interleukin-1a on basal gonadotropin release in the ovariectomized rhesus monkey: reversal by a corticotropin-releasing factor antagonist. Endocrinology. 1991 Apr;128(4):2077-82. DOI:10.1210/endo-128-4-2077 |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
|