| Identification | Back Directory | [Name]
IOMJPRIMVDNEHH-IYARVYRRSA-N | [CAS]
1507362-00-6 | [Synonyms]
IOMJPRIMVDNEHH-IYARVYRRSA-N
Propanamide, 3-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]-N-[trans-4-(5-phenyl-1,3,4-oxadiazol-2-yl)cyclohexyl]- | [Molecular Formula]
C25H25N5O3S | [MOL File]
1507362-00-6.mol | [Molecular Weight]
475.56 |
| Hazard Information | Back Directory | [Uses]
TNKS 22 (compound 22) is an orally active and selective tankyrase inhibitor. TNKS 22 inhibits TNKS1 and TNKS2 with IC50s of 0.1 and 4.1 nM, respectively[1]. | [References]
[1] Hua Z, et al. Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors. J Med Chem. 2013 Dec 27;56(24):10003-15. DOI:10.1021/jm401317z |
|
|