| Identification | Back Directory | [Name]
CP 135807 | [CAS]
151272-90-1 | [Synonyms]
CP 135807
3-(N-Methylpyrrolidin-2R-ylmethyl)-5-(3-nitropyrid-2- yl)amino-1H-indole
(R)-3-[(1-Methyl-2-pyrrolidinyl)Methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-aMine
3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-N-(3-nitropyridin-2-yl)-1H-indol-5-amine
3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine
1H-Indol-5-amine, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-N-(3-nitro-2-pyridinyl)- | [Molecular Formula]
C19H21N5O2 | [MDL Number]
MFCD00921453 | [MOL File]
151272-90-1.mol | [Molecular Weight]
351.4 |
| Chemical Properties | Back Directory | [Melting point ]
158-161°C | [storage temp. ]
Store at +4°C | [solubility ]
DMSO: ≥5mg/mL | [form ]
powder | [color ]
brown-red | [Optical Rotation]
[α]/D +100 to +120°, c = 0.025 mg/mL in methanol | [InChI]
1S/C19H21N5O2/c1-23-9-3-4-15(23)10-13-12-21-17-7-6-14(11-16(13)17)22-19-18(24(25)26)5-2-8-20-19/h2,5-8,11-12,15,21H,3-4,9-10H2,1H3,(H,20,22)/t15-/m1/s1 | [InChIKey]
YPFIYPNOWVPAPR-OAHLLOKOSA-N | [SMILES]
CN1CCC[C@@H]1Cc2c[nH]c3ccc(Nc4ncccc4[N+]([O-])=O)cc23 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22-36/37/38 | [Safety Statements ]
26 | [WGK Germany ]
3 | [RTECS ]
NL2412000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Dark Brown Solid | [Uses]
A selective 5-HT1D receptor agonist. | [Biological Activity]
Selective 5-HT 1D receptor agonist. Produces dose-dependent decreases in extracellular 5-HT concentration. | [in vivo]
Pigeons were trained to peck a key under a multiple fixed-ratio 25 fixed-ratio 175 schedule of food presentation. CP-135807 (0.1 mg/kg; i.m.; single dose) fully and dose-dependently substitutes for the training dose in adult male Carneau pigeons[1].
| [IC 50]
5-HT1D Receptor: 3.1 nM (IC50, rat); 5-HT1D Receptor: 33 nM (IC50, bovine) | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|