| Identification | Back Directory | [Name]
N-(4-AMinobutyl)biotinaMide | [CAS]
151294-96-1 | [Synonyms]
Biotin-C4-amide-C5-NH2
N-(4-AMinobutyl)biotinaMide
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(4-aminobutyl)hexahydro-2-oxo-, (3aS,4S,6aR)-
N-(4-Aminobutyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide | [Molecular Formula]
C14H26N4O2S | [MDL Number]
MFCD28397129 | [MOL File]
151294-96-1.mol | [Molecular Weight]
314.45 |
| Chemical Properties | Back Directory | [Boiling point ]
650.1±50.0 °C(Predicted) | [density ]
1.148±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [form ]
Solid | [pka]
13.90±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [Biological Activity]
Biotin-C4-amide-C5-NH2 is a cleavable ADC linker that can be used to synthesize antibody-drug conjugates (ADCs). | [in vitro]
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | [target]
| [IC 50]
Cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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