| Identification | Back Directory | [Name]
2-(2,4-Difluorophenyl)-3-methyl-1-(1H-1,2,4-triazol-1-yl)-3-(6-(1H-1,2,4-triazol-1-yl)pyridazin- 3-ylthio)butan-2-ol | [CAS]
151856-47-2 | [Synonyms]
MFB 1041
2-(2,4-Difluorophenyl)-3-methyl-1-(1H-1,2,4-triazol-1-yl)-3-(6-(1H-1,2,4-triazol-1-yl)pyridazin- 3-ylthio)butan-2-ol
1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-[1-methyl-1-[[6-(1H-1,2,4-triazol-1-yl)-3-pyridazinyl]thio]ethyl]-, (+)- | [Molecular Formula]
C19H18F2N8OS | [MOL File]
151856-47-2.mol | [Molecular Weight]
444.46 |
| Hazard Information | Back Directory | [Description]
Mfb 1041 is a triazol antifungal agent. | [Uses]
MFB-1041 is an orally active antifungal agent, but exhibits poor oral absorption. MFB-1041 induces the binding of drug to serum albumin[1][2]. | [References]
[1] Kai T, et al., Oral absorption improvement of poorly soluble drug using solid dispersion technique. Chem Pharm Bull (Tokyo). 1996 Mar;44(3):568-71. DOI:10.1248/cpb.44.568
[2] Miyoshi T, et al. Effect of maltosyl-beta-cyclodextrin on drug binding to serum albumin[J]. 1997. |
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