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152323-73-4

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152323-73-4 Structure

152323-73-4 Structure
IdentificationBack Directory
[Name]

GR 83895
[CAS]

152323-73-4
[Synonyms]

GR 83895
[Molecular Formula]

C29H39N9O8S
[MOL File]

152323-73-4.mol
[Molecular Weight]

673.74
Chemical PropertiesBack Directory
[density ]

1?+-.0.1 g/cm3(Predicted)
[pka]

4.00±0.10(Predicted)
Hazard InformationBack Directory
[Description]

GR 83895 is a prototype fibrinogen receptor antagonist.
[Uses]

GR83895 is a RGD based peptide, and inhibits ADP-induced platelet aggregation of human gel-filtered platelets (IC50= 0.9 μM)[1].
[References]

[1] Foster MR, et al. Improved potency and specificity of Arg-Gly-Asp (RGD) containing peptides as fibrinogen receptor blocking drugs. Thromb Res. 1993 Nov 1;72(3):231-45. DOI:10.1016/0049-3848(93)90190-y
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