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152459-94-4

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152459-94-4 Structure

152459-94-4 Structure
IdentificationBack Directory
[Name]

CGP-53716
[CAS]

152459-94-4
[Synonyms]

CGP-53716
N-(4-methyl-3(4-(pyridine-3-yl)pyrimidin-2-ylamino)phenyl)benzamide
N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Benzamide, N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-
[Molecular Formula]

C23H19N5O
[MDL Number]

MFCD00945675
[MOL File]

152459-94-4.mol
[Molecular Weight]

381.43
Chemical PropertiesBack Directory
[storage temp. ]

under inert gas (nitrogen or Argon) at 2–8 °C
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

CGP 53716 is a potent protein tyrosine kinase inhibitor. CGP 53716 has selective activity of platelet-derived growth factor (PDGF) receptor. CGP 53716 can be used in the study of disease induced by abnormal cell proliferation induced by PDGF receptor activation [1].
[References]

[1] Buchdunger E, et al. Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2558-62. DOI:10.1073/pnas.92.7.2558
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