| Identification | Back Directory | [Name]
Leachianone G | [CAS]
152464-78-3 | [Synonyms]
Leachianone G
(2S)-2-(2,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-8-(3-methyl-2-buten-1-yl)-, (2S)- | [Molecular Formula]
C20H20O6 | [MOL File]
152464-78-3.mol | [Molecular Weight]
356.37 |
| Chemical Properties | Back Directory | [Boiling point ]
639.6±55.0 °C(Predicted) | [density ]
1.384±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
7.65±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Leachianone G is an antiviral flavonoid from the root bark of Morus alba L. Leachianone G shows potent antiviral activity against herpes simplex type 1 virus (HSV-1) with an IC50 value of 1.6 μg/mL[1]. | [Definition]
ChEBI: Leachianone G is a tetrahydroxyflavanone having the hydroxy groups at the 2'-, 4'-, 5- and 7-positions and a prenyl group at 8-position. It is a tetrahydroxyflavanone, a member of 4'-hydroxyflavanones and a (2S)-flavan-4-one. It is functionally related to a (S)-naringenin. It is a conjugate acid of a leachianone G(1-). | [IC 50]
HSV-1: 1.6 μg/mL (IC50) | [References]
[1] Du J, et al. Antiviral flavonoids from the root bark of Morus alba L. Phytochemistry. 2003 Apr;62(8):1235-8. DOI:10.1016/s0031-9422(02)00753-7 |
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