| Identification | Back Directory | [Name]
WIN 62005 | [CAS]
152633-54-0 | [Synonyms]
WIN 62005
2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-5-methyl-6-(4-pyridinyl)- | [Molecular Formula]
C12H10N4O | [MDL Number]
MFCD00929090 | [MOL File]
152633-54-0.mol | [Molecular Weight]
226.23 |
| Hazard Information | Back Directory | [Uses]
Win-62005 is a cyclic AMP phosphodiesterase III (PDE III) inhibitor with Kis of 25 and 26 nM for rat heart and canine aorta, respectively. | [in vivo]
After p.o. administration of 1 mg/kg Win-62005, LVdP/dtmax is significantly increased in 30 min and remains increased for at least 6 h[1]. | [References]
[1] Dundore RL, et al. Species-dependent pharmacodynamic effects of the selective low Km cyclic AMP phosphodiesterase III inhibitors WIN 58993 and WIN 62005. J Cardiovasc Pharmacol. 1995 Jan;25(1):14-21. DOI:10.1097/00005344-199501000-00004 |
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|