| Identification | Back Directory | [Name]
hemorphin 7 | [CAS]
152685-85-3 | [Synonyms]
L-Phenylalanine, L-tyrosyl-L-prolyl-L-tryptophyl-L-threonyl-L-glutaminyl-L-arginyl- | [Molecular Formula]
C49H64N12O11 | [MOL File]
152685-85-3.mol | [Molecular Weight]
997.11 |
| Chemical Properties | Back Directory | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
3.50±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
Water : 12.5 mg/mL (12.54 mM) | [Sequence]
Tyr-Pro-Trp-Thr-Gln-Arg-Phe |
| Hazard Information | Back Directory | [Uses]
Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors and inhibiting angiotensin-converting enzyme (ACE). | [References]
[1] Dejouvencel T, et al. Hemorphin 7 reflects hemoglobin proteolysis in abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):269-75. DOI:10.1161/ATVBAHA.109.198309 |
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