| Identification | Back Directory | [Name]
Seco-Duocarmycin SA | [CAS]
152785-82-5 | [Synonyms]
Seco-Duocarmycin SA
(S)-Seco-Duocarmycin SA | [Molecular Formula]
C25H24ClN3O7 | [MDL Number]
MFCD29127463 | [MOL File]
152785-82-5.mol | [Molecular Weight]
513.93 |
| Chemical Properties | Back Directory | [Boiling point ]
773.9±60.0 °C(Predicted) | [density ]
1.458±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
9.69±0.40(Predicted) | [color ]
Light yellow to yellow | [InChIKey]
SDJNZXKVYYJDDM-GFCCVEGCSA-N | [SMILES]
N1C(C(OC)=O)=CC2=C3[C@H](CCl)CN(C(C4=CC5=C(N4)C(OC)=C(OC)C(OC)=C5)=O)C3=CC(O)=C12 |
| Hazard Information | Back Directory | [Uses]
(S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates[1]. | [storage]
Store at -20°C | [References]
[1] Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69. DOI:10.1021/ja072777z |
|
| Company Name: |
Abydos Scientific
|
| Tel: |
025-84767922 18936879710 |
| Website: |
http://www.abydoscientific.com/index.html |
| Company Name: |
YJ Pharma
|
| Tel: |
13962794339 |
| Website: |
|
|