| Identification | Back Directory | [Name]
IB-MECA | [CAS]
152918-18-8 | [Synonyms]
CF-101
IB-MECA
CS-2564
RPR-113090
Selepressin
PICLIDENOSON;CF-101
Piclidenoson (IB-MECA)
IBMECA;(PICLIDENOSON; CF-101
IB-MECA SELECTIVE A3 ADENOSIN
N6-(3-IODOBENZYL)ADO-5'N-METHYLURONAMIDE
3-iodobenzyl-5'-N-methylcarboxamidoadenosine
N6-(3-iodo-benzyl)adenosine-5'-N-MethyluronaMide
n(6)-(3-iodobenzyl)-5’-n-methylcarboxamidoadenosine
1-deoxy-1-[6-[((3-iodophenyl)methyl)amino]-9h-purin-9-yl]-n-methyl-β-d-ribofuranuronamide
β-D-Ribofuranuronamide, 1-deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-
b-D-RibofuranuronaMide, 1-deoxy-1-[6-[[(3-iodophenyl)Methyl]aMino]-9H-purin-9-yl]-N-Methyl-
1-DEOXY-1-[6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-N-METHYL-BETA-D-RIBOFURANURON-AMIDE
(2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide
N6-(3-Iodobenzyl)adenosine-5μ-N-methyluronamide, 1-Deoxy-1-[6-[((3-Iodophenyl)methyl)amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide | [Molecular Formula]
C18H19IN6O4 | [MDL Number]
MFCD00671785 | [MOL File]
152918-18-8.mol | [Molecular Weight]
510.29 |
| Chemical Properties | Back Directory | [density ]
1.98±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
hot ethanol: >10 mg/mL
| [form ]
solid
| [pka]
12.72±0.70(Predicted) | [color ]
white
| [InChIKey]
HUJXGQILHAUCCV-MOROJQBDSA-N | [SMILES]
CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4cccc(I)c4)ncnc23 |
| Hazard Information | Back Directory | [Uses]
IB-MECA has been used for intraocular pressure and corneal thickness measurements in rabbits. | [Definition]
ChEBI: A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and one of the hydrogens of the exocyclic amino function is substituted by a 3-iodobenzyl group. | [Biological Activity]
Potent and selective A 3 adenosine receptor agonist (K i values are 1.1, 54 and 56 nM for A 3 , A 1 and A 2A receptors respectively). Cardioprotective, reduces infarct size upon reperfusion in rats. | [Biochem/physiol Actions]
Selective A3 adenosine receptor agonist. | [storage]
Desiccate at +4°C |
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