1531594-08-7

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1531594-08-7 Structure

Identification	Back Directory
[Name] Tesidolumab
[CAS] 1531594-08-7
[Synonyms] Tesidolumab Tesidolumab (anti-Complement C5) Research Grade Tesidolumab (DHB90004)

Chemical Properties	Back Directory
[form ] Liquid
[color ] Colorless to light yellow

Hazard Information	Back Directory
[Uses] Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex[1].
[References] [1] Jun-Ichi Nishimura, et al. Tesidolumab (LFG316) for treatment of C5-variant patients with paroxysmal nocturnal hemoglobinuria. Haematologica. 2022 Jun 1;107(6):1483-1488. DOI:10.3324/haematol.2020.265868

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