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153190-63-7

153190-63-7 Structure

153190-63-7 Structure
IdentificationBack Directory
[Name]

AXL
[CAS]

NoCAS
[Synonyms]

AXL
Ark
Ufo
JTK11
Axl active human
Human AXL Protein, His Tag
Tyrosine-protein kinase receptor UFO
AXL (473-end), active, His tagged human
Monoclonal Anti-AXL antibody produced in mouse
ANTI-MOUSE AXL (N-TERM) antibody produced in rabbit
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

buffered aqueous solution
[biological source]

mouse
[Specific Activity]

88-120nmol/min·mg
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

10 - Combustible liquids
Hazard InformationBack Directory
[Uses]

Monoclonal Anti-AXL antibody has been used in
  • immunoblotting
  • immunocytochemistry
  • immunofluorescence
  • flow cytometry

[Biological Activity]

AXL is a member of the receptor tyrosine kinase family which has oncogenic potential and is implicated in human myeloid leukemia. AXL is a member of a complex signaling network th at is involved in the control of cell proliferation and differentiation. Overexpression of AXL cDNA in NIH 3T3 cells induces neoplastic transformation of these cells with the concomitant appearance of a 140 kDa AXL tyrosine-phosphorylated protein. Expression of AXL cDNA in the baculovirus system results in the expression of the appropriate recombinant protein th at is recognized by antiphosphotyrosine antibodiesconfirming th at the AXL protein is tyrosine phosphorylated.
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