| Identification | Back Directory | [Name]
2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-sulfooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid | [CAS]
15324-64-8 | [Synonyms]
Sulfolithocholylglycine
Glycine, N-[(3α,5β)-24-oxo-3-(sulfooxy)cholan-24-yl]-
2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-sulfooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid | [Molecular Formula]
C26H43NO7S | [MOL File]
15324-64-8.mol | [Molecular Weight]
513.69 |
| Hazard Information | Back Directory | [Uses]
Sulfoglycolithocholic acid can be used in biochemical research and metabolomics research. It can be used to study the metabolism of bile acids, the gut microbiome, and the effects of bile acids on various tissues and organs. | [Definition]
ChEBI: The 3-O-sulfo derivative of glycolithocholic acid. | [in vivo]
Glycolithocholic acid 3-sulfate (24 μmoL /100 g; i.v., once) induces intrahepatic cholestasis and increases biliary cholesterol secretion in male Wistar rats with bile fistula[2]. | Animal Model: | Male Wistar rats with bile fistula[2] | | Dosage: | 24 μmoL/100 g | | Administration: | Intravenous injection; 24 μmoL/100 g | | Result: | Induced intrahepatic cholestasis and increased biliary cholesterol secretion. |
| [IC 50]
Microbial Metabolite |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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