| Identification | Back Directory | [Name]
aquastatin A | [CAS]
153821-50-2 | [Synonyms]
aquastatin A
Benzoic acid, 4-(β-D-galactopyranosyloxy)-2-hydroxy-6-pentadecyl-, 4-carboxy-3-hydroxy-5-methylphenyl ester | [Molecular Formula]
C36H52O12 | [MOL File]
153821-50-2.mol | [Molecular Weight]
676.79 |
| Chemical Properties | Back Directory | [Boiling point ]
836.5±65.0 °C(Predicted) | [density ]
1.269±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble | [form ]
A solid | [pka]
2.60±0.25(Predicted) |
| Hazard Information | Back Directory | [Uses]
Aquastatin A is an inhibitor of mammalian adenosine triphosphatases. Aquastatin A is isolated from a fungus identified as Fusarium aquaeductuum. Aquastatin A inhibits Na+/K(+)-ATPase with an IC50 value of 7.1 μM, and H+/K(+)-ATPase with an apparent IC50 value of 6.2 μM[1]. | [storage]
-20°C | [References]
[1] Hamano K, et al. Aquastatin A, an inhibitor of mammalian adenosine triphosphatases from Fusarium aquaeductuum. Taxonomy, fermentation, isolation, structure determination and biological properties. J Antibiot (Tokyo). 1993;46(11):1648-1657. DOI:10.7164/antibiotics.46.1648 |
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