| Identification | Back Directory | [Name]
4H-Imidazol-4-one, 5-[(3,5-difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-3-methyl-2-(trifluoromethyl)-, (5Z)- | [CAS]
1539318-40-5 | [Synonyms]
DFHBI-2T
4H-Imidazol-4-one, 5-[(3,5-difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-3-methyl-2-(trifluoromethyl)-, (5Z)- | [Molecular Formula]
C12H7F5N2O2 | [MOL File]
1539318-40-5.mol | [Molecular Weight]
306.19 |
| Chemical Properties | Back Directory | [Boiling point ]
285.6±50.0 °C(Predicted) | [density ]
1.54±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
6.62±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
DFHBI-2T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=500 nm/523 nm). DFHBI-2T is used to image RNA in live cells[1][2]. | [References]
[1] Wenjiao Song, et al. Plug-and-play fluorophores extend the spectral properties of Spinach. J Am Chem Soc. 2014 Jan 29;136(4):1198-201. DOI:10.1021/ja410819x
[2] Robert J Trachman 3rd, et al. Structural Principles of Fluorescent RNA Aptamers. Trends Pharmacol Sci. 2017 Oct;38(10):928-939. DOI:10.1016/j.tips.2017.06.007 |
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