| Identification | Back Directory | [Name]
2,5,7,8-Tetramethyl-2-(piperazine-1-carbonyl)-3,4-dihydro-2H-1-benzopyran-6-ol hydrochloride | [CAS]
1541170-25-5 | [Synonyms]
Sul121 HCl
Sul-121 HCl
Sul 121 HCl
Sul-121 Hydrochloride
2,5,7,8-Tetramethyl-2-(piperazine-1-carbonyl)-3,4-dihydro-2H-1-benzopyran-6-ol hydrochloride | [Molecular Formula]
C18H27ClN2O3 | [MDL Number]
MFCD28506648 | [MOL File]
1541170-25-5.mol | [Molecular Weight]
354.88 |
| Hazard Information | Back Directory | [Description]
Sul-121 is a novel compound with anti-oxidative capacity. Sul-121 HCl inhibits airway inflammation and hyperresponsiveness (AHR) in experimental chronic obstructive pulmonary disease (COPD) models, prospectively through inhibition of oxidative stress. | [Uses]
Sul-121 hydrochloride is a novel compound with anti-oxidative capacity that effectively inhibits airway inflammation and hyperresponsiveness (AHR) in experimental models of chronic obstructive pulmonary disease (COPD). Sul-121 hydrochloride prevents lipopolysaccharide-induced airway neutrophilia and AHR in a dose-dependent manner. Sul-121 hydrochloride also demonstrates the ability to reduce oxidative stress markers in human airway smooth muscle cells. Sul-121 hydrochloride inhibits nuclear translocation of the NF-κB subunit, p65, thereby diminishing pro-inflammatory cytokine release. | [References]
[1] The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease DOI:10.1038/srep26928 |
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| Company Name: |
Matrix Scientific
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803 788-9494 All other calls |
| Website: |
www.matrixscientific.com |
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