| Identification | Back Directory | [Name]
Carfilzomib Impurity 2 | [CAS]
1541172-75-1 | [Synonyms]
PR-519
Kyprolis Impurity V
L-Phenylalaninamide, (αS)-α-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S,3R)-3,4-dihydroxy-3-methyl-1-(2-methylpropyl)-2-oxobutyl]-
(S)-N-((S)-1-(((2R,4S)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pe
(S)-N-((S)-1-(((2R,4S)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide | [Molecular Formula]
C40H59N5O8 | [MOL File]
1541172-75-1.mol | [Molecular Weight]
737.93 |
| Chemical Properties | Back Directory | [Boiling point ]
1023.6±65.0 °C(Predicted) | [density ]
1.173±0.06 g/cm3(Predicted) | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
12.12±0.29(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic | [InChIKey]
ABPYUKBBMCBILQ-RVAZOSSWNA-N | [SMILES]
C(NC(CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(=O)[C@](O)(C)CO)=O)(=O)[C@@H](NC(=O)[C@@H](NC(CN1CCOCC1)=O)CCC1=CC=CC=C1)CC(C)C |&1:12,19,26,30,r| |
| Hazard Information | Back Directory | [Uses]
Carfilzomib (2R,4S)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. |
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BOC Sciences
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Lynnchem
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Novachemistry
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Abydos Scientific
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