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1542098-94-1

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1542098-94-1 Structure

1542098-94-1 Structure
IdentificationBack Directory
[Name]

DHQZ 36
[CAS]

1542098-94-1
[Synonyms]

DHQZ 36
[Molecular Formula]

C21H18F2N2OS
[MDL Number]

MFCD32671338
[MOL File]

1542098-94-1.mol
[Molecular Weight]

384.44
Chemical PropertiesBack Directory
[Boiling point ]

568.9±50.0 °C(Predicted)
[density ]

1.311±0.06 g/cm3(Predicted)
[pka]

0.71±0.40(Predicted)
Hazard InformationBack Directory
[Description]

DHQZ-36 is a retrograde trafficking inhibitor. It acts by protecting cells from infections by human polyoma- and papillomaviruses.
[Uses]

DHQZ 36 is a potent inhibitor of retrograde trafficking. DHQZ 36 inhibits Leishmania amazonensis infection in macrophages with an EC50 of 13.63 μM. DHQZ 36 has potent anti-parasite activity[1].
[References]

[1] Craig E, et al. Structurally optimized analogs of the retrograde trafficking inhibitor Retro-2cycl limit Leishmania infections. PLoS Negl Trop Dis. 2017 May 15;11(5):e0005556. DOI:10.1371/journal.pntd.0005556
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