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154446-98-7

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154446-98-7 Structure

154446-98-7 Structure
IdentificationBack Directory
[Name]

LY 222306
[CAS]

154446-98-7
[Synonyms]

LY 222306
XRFATXPLBQDDGE-ACGXKRRESA-N
[Molecular Formula]

C19H23N5O7
[MDL Number]

MFCD31689301
[MOL File]

154446-98-7.mol
[Molecular Weight]

433.415
Chemical PropertiesBack Directory
[density ]

1.67±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

3.51±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
[storage]

Store at -20°C
[References]

[1] Habeck LL, et al. A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer Res. 1994 Feb 15;54(4):1021-6. PMID:8313357
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Company Name: TargetMol Chemicals Inc.
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