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154447-41-3

154447-41-3 Structure

154447-41-3 Structure
IdentificationBack Directory
[Name]

L 366763
[CAS]

154447-41-3
[Synonyms]

763
L 366763
[Molecular Formula]

C29H48N12O11S2
[MOL File]

154447-41-3.mol
[Molecular Weight]

804.895
Chemical PropertiesBack Directory
[Sequence]

Ac-Cys-Asn-Pro-Arg-Gly-Asp-Cys-NH2
Hazard InformationBack Directory
[Description]

L 366763 is a peptidyl fibrinogen receptor antagonist.
[Uses]

L 366763 is a potent peptide that acts as a fibrinogen receptor antagonist, preventing collagen-induced platelet aggregation and adhesion. L 366763 inhibits platelet deposition and maintains blood flow in a baboon thrombosis model, significantly prolonging bleeding time. L 366763 has antithrombotic efficacy, whereas recombinant LAPP does not have the same effect[1].
[References]

[1] Recombinant Leech Antiplatelet Protein Prevents Collagen-Mediated Platelet Aggregation but Not Collagen Graft Thrombosis in Baboons
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