| Identification | Back Directory | [Name]
1 1-DIMETHYLBIGUANIDE HYDROCHLORIDE | [CAS]
15537-72-1 | [Synonyms]
1,1-DIMETHYLBIGUANIDE HYDROCHLORIDE
1，1-Dimethylbiguanide Hydrochloride-D6 | [EINECS(EC#)]
605-006-2 | [Molecular Formula]
C4H11N5 | [MOL File]
15537-72-1.mol | [Molecular Weight]
165.62 |
| Chemical Properties | Back Directory | [Melting point ]
223-226 °C(lit.)
| [InChI]
InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H | [InChIKey]
OETHQSJEHLVLGH-UHFFFAOYSA-N | [SMILES]
N(C)(C)C(NC(N)=N)=N.[H]Cl | [CAS DataBase Reference]
15537-72-1 |
| Questions And Answer | Back Directory | [Uses]
Metformin hydrochloride can be used for the following purposes: 1. Type 2 diabetic patients whose condition is not adequately controlled by diet alone (for obese patients and those with hyperinsulinemia, this drug not only lowers blood sugar but also helps reduce weight and alleviate hyperinsulinemia); 2. Certain diabetic patients who respond poorly to sulfonylureas (it can be used in combination with sulfonylureas). |
| Hazard Information | Back Directory | [Originator]
Diabetex ,Germania | [Definition]
ChEBI: Metformin hydrochloride is a hydrochloride resulting from the reaction of metformin with one molar equivalent of hydrogen chloride. It has a role as an environmental contaminant, a hypoglycemic agent and a xenobiotic. It contains a metformin(1+). | [Manufacturing Process]
The boiling mixture of 1,000 L xylene, 450 kg dimethylamine and 840 kg dicyanamide was added 365 kg hydrogene chloride. Yield of biguanide, 1,1- dimethyl-, hydrochloride 1,588 kg (96%). Biguanide, 1,1-dimethyl-, hydrochloride may be recrystallysed from methanol. | [Therapeutic Function]
Oral hypoglycemic |
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