| Identification | Back Directory | [Name]
Benzene, 1-chloro-2-[(1E)-2-[(2-methoxyphenyl)sulfonyl]ethenyl]- | [CAS]
1554271-18-9 | [Synonyms]
Nrf2 Activator IV
Nrf2 Activator-IV
Nrf2-Activator-12G
Benzene, 1-chloro-2-[(1E)-2-[(2-methoxyphenyl)sulfonyl]ethenyl]- | [Molecular Formula]
C15H13ClO3S | [MDL Number]
MFCD31800430 | [MOL File]
1554271-18-9.mol | [Molecular Weight]
308.78 |
| Chemical Properties | Back Directory | [Boiling point ]
506.4±50.0 °C(Predicted) | [density ]
1.308±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 100mg/mL | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Nrf2-Activator-12G is a potent Nrf-2 activator. | [Uses]
Nrf2-Activator-12G (compd 12g) is an activator of Nrf2. Nrf2-Activator-12G induces the expression of nrf2-dependentantioxidant enzymes at both mRNA and protein levels in DAergic neuronal cell. Nrf2-Activator-12G can used in study Parkinson’s Disease[1]. | [References]
[1] Woo SY, et al. Discovery of vinyl sulfones as a novel class of neuroprotective agents toward Parkinson's disease therapy. J Med Chem. 2014 Feb 27;57(4):1473-87. DOI:10.1021/jm401788m |
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