ChemicalBook--->CAS DataBase List--->155575-02-3

155575-02-3

155575-02-3 Structure

155575-02-3 Structure
IdentificationBack Directory
[Name]

L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
[CAS]

155575-02-3
[Synonyms]

Pyr-RTKR-AMC
PYR-ARG-THR-LYS-ARG-MCA
50:PN:WO0042071 FIGURE:18 claimed protein
PGLU-ARG-THR-LYS-ARG 7-AMIDO-4-METHYLCOUMARIN
PYROGLU-ARG-THR-LYS-ARG-7-AMIDO-4-METHYLCOUMARIN
L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
L-Argininamide, 5-oxo-L-prolyl-L-arginyl-L-threonyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
[Molecular Formula]

C37H57N13O9
[MDL Number]

MFCD00210688
[MOL File]

155575-02-3.mol
[Molecular Weight]

827.93
Chemical PropertiesBack Directory
[density ]

1.51±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[pka]

12.47±0.20(Predicted)
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Pyr-Arg-Thr-Lys-Arg-AMC is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors[1].
[References]

[1] Neugebauer WA, et al. C-terminal amidation on aryl hydrazine resin. Adv Exp Med Biol. 2009;611:371-2. DOI:10.1007/978-0-387-73657-0_164
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