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155918-12-0

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155918-12-0 Structure

155918-12-0 Structure
IdentificationBack Directory
[Name]

H-THR-ARG-SER-ALA-TRP-NH2
[CAS]

155918-12-0
[Synonyms]

THR-ARG-SER-ALA-TRP-NH2
H-THR-ARG-SER-ALA-TRP-NH2
H-Thr-Arg-Ser-Ala-Trp-NH2L-
Human osteostatin(1-5) amide
PTH-RP (107-111) AMIDE (HUMAN, RAT)
PTH-RELATED PROTEIN (107-111) AMIDE (HUMAN, RAT)
L-Tryptophanamide, L-threonyl-L-arginyl-L-seryl-L-alanyl-
D-Allothreonyl-D-arginyl-L-seryl-D-alanyl-L-tryptophanamide
HYPERCALCEMIA OF MALIGNANCY FACTOR (107-111) AMIDE (HUMAN, RAT)
PARATHYROID HORMONE-RELATED PROTEIN (107-111) AMIDE (HUMAN, RAT)
PTH-RP (107-111) AMIDE (HUMAN, BOVINE, DOG, HORSE, MOUSE, RABBIT, RAT)
OSTEOSTATIN (1-5) AMIDE (HUMAN, BOVINE, DOG, HORSE, MOUSE, RABBIT, RAT)
PTH-RELATED PROTEIN (107-111) AMIDE (HUMAN, BOVINE, DOG, HORSE, MOUSE, RABBIT, RAT)
HYPERCALCEMIA OF MALIGNANCY FACTOR (107-111) AMIDE (HUMAN, BOVINE, DOG, HORSE, MOUSE, RABBIT, RAT)
Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt H-Thr-Arg-Ser-Ala-Trp-NH2 trifluoroacetate salt
HypercalceMia of Malignancy Factor (107-111) aMide (huMan, bovine, dog, horse, Mouse, rabbit, rat), pTH-Related Protein (107-111) aMide (huMan, bovine, dog, horse, Mouse, rabbit, rat), pTH-rP (107-111) aMide (huMan, bovine, dog, horse, Mouse, rabbit, rat)
[Molecular Formula]

C27H42N10O7
[MDL Number]

MFCD00145492
[MOL File]

155918-12-0.mol
[Molecular Weight]

618.69
Chemical PropertiesBack Directory
[density ]

1.53±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[pka]

12.10±0.45(Predicted)
[Sequence]

Thr-Arg-Ser-Ala-Trp-NH2
Hazard InformationBack Directory
[Uses]

Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroid hormone-related protein fragment that can inhibit bone resorption[1][2].
[References]

[1] Murrills RJ, et al. Lack of significant effect of carboxyl-terminal parathyroid hormone-related peptide fragments on isolated rat and chick osteoclasts. Calcif Tissue Int. 1995 Jul;57(1):47-51. DOI:10.1007/BF00298996
[2] Whitfield JF, et al. C-terminal fragments of parathyroid hormone-related protein, PTHrP-(107-111) and (107-139), and the N-terminal PTHrP-(1-40) fragment stimulate membrane-associated protein kinase C activity in rat spleen lymphocytes. J Cell Physiol. 1994 Mar;158(3):518-22. DOI:10.1002/jcp.1041580317
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