| Identification | Back Directory | [Name]
YOYO 3 | [CAS]
156312-20-8 | [Synonyms]
YOYO 3
Yoyo 3 Iodide
DiYO-3 (equivalent to YO-YO 3) *5 mM DMSO Solution* *CAS 156312-20-8*
QUINOLINIUM, 1,1'-[1,3-PROPANEDIYLBIS[(DIMETHYLIMINIO)-3,1-PROPANEDIYL]]BIS[4-[3-(3-METHYL-2(3H)-BENZOXAZOLYLIDENE)-1-PROPENYL]-, TETRAIODIDE
Quinolinium, 1,1
0
-[1,3-propanediylbis
[(dimethyliminio)-3,1-propanediyl]]bis[4-[3-(3-methyl-2
(3h)-benzoxazolylidene)-1-propenyl]-, Tetraiodide
2-((E)-3-[1-(3-[(3-[DIMETHYL(3-(4-[(Z,2E)-3-(3-METHYL-1,3-BENZOXAZOL-3-IUM-2-YL)-2-PROPENYLIDENE]-1-QUINOLINYL)PROPYL)AMMONIO]PROPYL)(DIMETHYL)AMMONIO]PROPYL)-4(1H)-QUINOLINYLIDENE]-1-PROPENYL)-3-METHYL-1,3-BENZOXAZOL-3-IUM TETRAIODIDE | [Molecular Formula]
C53H62IN6O2+3 | [MDL Number]
MFCD03788223 | [MOL File]
156312-20-8.mol | [Molecular Weight]
942.02 |
| Chemical Properties | Back Directory | [Melting point ]
>250 ℃ | [solubility ]
Soluble in dimethyl sulfoxide | [form ]
powder | [color ]
Orange-red | [Appearance]
dark violet solution | [ex/em]
612/631 nm | [ε(extinction coefficient)]
167000 cm−1M−1 | [λmax]
612 nm | [Φ(quantum yield)]
0.15 | [Biological Applications]
Nucleic acid hybridization; detecting nucleic acids,ells,pathogens; counting embryoblasts; monitoring cell cycle kinetics | [Major Application]
Analyzing polymers |
| Hazard Information | Back Directory | [Description]
YODi-3 (Oxazole Red Homodimer, also known as YOYO®-3) is a red fluorescent carbocyanine dimeric dye. YODi-3 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits significant fluorescence enhancement upon binding to DNA.
The bright fluorescence signal and low background make YODi-3 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments.
Simultaneous labeling with cell-impermeant YODi-3 and cell-permeable LUCS 13 or Annexin V-AF488 can be used to assess cell viability and apoptosis. | [Chemical Properties]
ex/em: 612/631 nm
Extinction coefficient (ε): 167000 cm??1M??1
Quantum yield (Φ): 0.15 | [Uses]
YOYO-3 is a cell-impermeant dye with far-red fluorescence used as nulear counterstain and dead cell indicator. It generates bright fluorescence upon binding to DNA. | [Abs/Em Maxima]
612/631 nm | [Excitation / Emission Maximum]
612 nm/631 nm |
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