| Identification | Back Directory | [Name]
1-Bromo-4-ethoxy-2,3-difluorobenzene | [CAS]
156573-09-0 | [Synonyms]
B90001
4-Bromo-2,3-difluorophenetole >
1-BROMO-4-ETHOXY-2,3-DIFLUOROBENZENE
1-Bromo-4-ethoxyl-2,3-difulorobenzene
2,3-Difluoro-4-bromophenylethyl ether
4-BroMo-2,3-difluorophenyl ethyl ether
Benzene, 1-bromo-4-ethoxy-2,3-difluoro-
5-broMo-1,2-difluoro-3-(MethoxyMethyl)benzene | [Molecular Formula]
C8H7BrF2O | [MDL Number]
MFCD07368018 | [MOL File]
156573-09-0.mol | [Molecular Weight]
237.04 |
| Chemical Properties | Back Directory | [Melting point ]
31 °C | [Boiling point ]
222.7±35.0 °C(Predicted) | [density ]
1.533±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
soluble in Methanol | [form ]
powder to lump | [color ]
White to Almost white | [InChIKey]
OJZVBJOHBGYINN-UHFFFAOYSA-N |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white crystalline | [Synthesis]
To an aqueous sodium hydroxide solution (400 ml) of 4-bromo-2,3-difluorophenol (T-1) (195.0 g), ethidium bromide (196.2 g), and tetrabutylammonium bromide (TBAB) (24.2 g) was added sodium hydroxide (75.9 g), and the reaction was heated and stirred under nitrogen protection for 6 hr at 80 °C. After completion of the reaction, extraction was carried out with heptane and the organic layer was washed sequentially with water and saturated saline. Subsequently, the organic layer was dried with anhydrous magnesium sulfate and concentrated under reduced pressure to give a black oily substance. The oily substance was purified by distillation to give 1-ethoxy-2,3-difluorobromobenzene (T-2) as a colorless oily liquid (230.0 g, yield: 97%). | [References]
[1] Patent: EP2484658, 2012, A1. Location in patent: Page/Page column 37
[2] Patent: JP5663957, 2015, B2. Location in patent: Paragraph 0137-0138; 0139 |
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